Sarmiento R, Holubka J, Khatib R
St. John Hospital and Medical Center, Detroit, Michigan 48236.
Am J Med Sci. 1994 Feb;307(2):115-8. doi: 10.1097/00000441-199402000-00009.
Candida albicans meningitis developed in a 55-year-old diabetic female, 1 year after catheter-associated candidemia. It was characterized by a protracted course, lack of meningeal signs, and the presence of an intradural filling defect within the caudal canal. Complete resolution of this filling defect with antifungal therapy implies that it probably represented an inflammatory mass. The development of meningitis after self-limiting candidemia and similar intradural filling defects have not been reported previously.
一名55岁的糖尿病女性在导管相关性念珠菌血症发生1年后出现了白色念珠菌性脑膜炎。其特点是病程迁延、缺乏脑膜刺激征,并且在骶管内存在硬膜内充盈缺损。抗真菌治疗后该充盈缺损完全消失,这意味着它可能代表一种炎性肿块。自限性念珠菌血症后发生脑膜炎以及类似的硬膜内充盈缺损此前尚未见报道。