氟康唑治疗白色念珠菌性脊椎椎间盘炎。
Fluconazole therapy in Candida albicans spondylodiscitis.
作者信息
Rössel P, Schønheyder H C, Nielsen H
机构信息
Department of Medical Gastroenterology, Aalborg Hospital, Denmark.
出版信息
Scand J Infect Dis. 1998;30(5):527-30. doi: 10.1080/00365549850161601.
A case of Candida albicans spondylodiscitis in a 20-year-old female liver transplant recipient is reported. The patient was successfully treated with sequential therapy with liposomal amphotericin B and fluconazole. A review of the literature showed 10 cases of Candida albicans spondylodiscitis successfully treated either with fluconazole alone or a sequential therapy with amphotericin B and fluconazole. If long-term amphotericin B therapy is not feasible, a prolonged course of fluconazole in a daily dose of 200-400 mg may be considered as an alternative.
报告了一例20岁女性肝移植受者发生白色念珠菌性脊椎盘炎的病例。该患者接受脂质体两性霉素B和氟康唑序贯治疗，治疗成功。文献回顾显示，有10例白色念珠菌性脊椎盘炎患者单独使用氟康唑或接受两性霉素B与氟康唑序贯治疗均取得成功。如果长期使用两性霉素B治疗不可行，可考虑每日剂量为200 - 400毫克的氟康唑延长疗程作为替代方案。
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