Balashov V P, Balykova L A, Sedova D G, Belova L A, Sernov L N, Kostin Ia V
Eksp Klin Farmakol. 1994 Jan-Feb;57(1):30-2.
Acute experiments on unconscious rats have demonstrated that fructose-1,6-diphosphate, phosphoenolpyruvate and malate of sodium produced a marked antiarrhythmic activity in acute occlusive and reperfusion arrhythmias, prevented the development of ventricular fibrillation and tachycardias, considerably reduced the duration of arrhythmia paroxysms, but they were ineffective in ventricular extrasystole.
对无意识大鼠进行的急性实验表明,1,6 - 二磷酸果糖、磷酸烯醇丙酮酸和苹果酸钠在急性闭塞性和再灌注性心律失常中具有显著的抗心律失常活性,可预防心室颤动和心动过速的发生,显著缩短心律失常发作的持续时间,但对室性早搏无效。