Acha-Orbea H, MacDonald H R
Ludwig Institute for Cancer Research, Lausanne Branch, Epalinges, Switzerland.
Trends Microbiol. 1993 Apr;1(1):32-4. doi: 10.1016/0966-842x(93)90022-j.
Recent experiments with mouse mammary tumor virus indicate that expression of a virally encoded superantigen by B cells and its subsequent recognition by T cells are essential steps for amplification of infection and virus transmission. Preliminary results suggest that superantigens may also be expressed during retroviral infection in humans.