Callen J P
Department of Medicine, University of Louisville, Kentucky.
Dermatol Clin. 1994 Jan;12(1):201-6.
After proper classification of cutaneous lesions in LE patients and extensive evaluation, we can begin to approach effective therapy. Patients with CLE (DLE or SCLE) generally have a favorable prognosis and can be managed with safe yet effective therapy. Sunscreens are the most important topical therapy. Intralesional corticosteroids are an effective local adjunctive therapy, useful in bringing lesions under control. Systemic therapy with antimalarials, either used singly or in combination, is usually effective. When "standard" therapy fails, azathioprine, retinoids, or occasionally dapsone may be effective.
在对红斑狼疮（LE）患者的皮肤病变进行恰当分类并进行全面评估后，我们便可着手开展有效治疗。盘状红斑狼疮（DLE）或亚急性皮肤型红斑狼疮（SCLE）等皮肤型红斑狼疮（CLE）患者的预后通常较好，可采用安全有效的治疗方法进行管理。防晒是最重要的局部治疗方法。皮损内注射皮质类固醇是一种有效的局部辅助治疗方法，有助于控制皮损。单独或联合使用抗疟药进行全身治疗通常有效。当“标准”治疗失败时，硫唑嘌呤、维甲酸，或偶尔使用的氨苯砜可能有效。
