Jonkhoff A R, Huijgens P C, Schreuder W O, Teule G J, Heimans J J
Department of Hematology, Free University Hospital, Amsterdam, The Netherlands.
J Neurooncol. 1993 Aug;17(2):155-8. doi: 10.1007/BF01050217.
A patient is described with a testicular Non-Hodgkin's Lymphoma (NHL) presenting with panhypopituitarism caused by a hypophyseal localization. A 67Gallium scintigraphy showed avid uptake in the hypophyseal region. Obviously 67Gallium could reach the tumor, by the intravenous route, which was the reason to treat the patient with intravenous chemotherapy. A complete remission was induced, which seems to be lasting (+25 months). As far as we know this is the first report of panhypopituitarism caused by a hypophyseal NHL in the hypophysis and successfully treated by intravenous chemotherapy.
本文描述了一名患有睾丸非霍奇金淋巴瘤(NHL)的患者,该肿瘤位于垂体,导致全垂体功能减退。67镓闪烁扫描显示垂体区域有明显摄取。显然,67镓可通过静脉途径到达肿瘤,这也是对该患者进行静脉化疗的原因。诱导出完全缓解,且似乎持续存在(25个月)。据我们所知,这是首例关于垂体非霍奇金淋巴瘤导致垂体全垂体功能减退并通过静脉化疗成功治疗的报告。