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惊恐障碍与重度抑郁症的共病情况。

Comorbidity of panic and major depressive disorder.

作者信息

Reich J, Warshaw M, Peterson L G, White K, Keller M, Lavori P, Yonkers K A

机构信息

Department of Psychiatry, Brown University, Providence, RI 02912.

出版信息

J Psychiatr Res. 1993;27 Suppl 1:23-33. doi: 10.1016/0022-3956(93)90015-t.

DOI:10.1016/0022-3956(93)90015-t
PMID:8145180
Abstract

The objective of this report is to determine whether those patients with panic disorder who have current major depression disorder (MDD) differ from those who do not in terms of demographics, comorbid disorders, severity of illness, nature of symptoms of panic attacks and psychosocial functioning. The sample consisted of 182 patients with current or history of panic disorder measured by standardized interview techniques. For analysis these patients were then divided by presence or absence of current MDD. The two groups were not different in age, sex, or marital status, age of onset, or symptom characteristics of panic attacks. However, patients with MDD were more likely to have Social Phobia and Generalized Anxiety Disorder, been hospitalized, made suicide attempts or gestures, have poorer psychosocial functioning, and currently be experiencing panic with more severe symptoms. These findings are discussed in terms of previous literature in the area.

摘要

本报告的目的是确定那些目前患有重度抑郁症(MDD)的惊恐障碍患者与未患重度抑郁症的患者在人口统计学、共病障碍、疾病严重程度、惊恐发作症状的性质以及心理社会功能方面是否存在差异。样本包括182名通过标准化访谈技术测量的目前患有或有惊恐障碍病史的患者。为了进行分析,这些患者随后根据是否患有目前的重度抑郁症进行了分组。两组在年龄、性别、婚姻状况、发病年龄或惊恐发作的症状特征方面没有差异。然而,患有重度抑郁症的患者更有可能患有社交恐惧症和广泛性焦虑症,曾住院治疗,有自杀企图或行为,心理社会功能较差,并且目前正在经历症状更严重的惊恐发作。将根据该领域以前的文献对这些发现进行讨论。

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