Katoh N, Sasaki K, Shibata T, Obazawa H, Fujiwara T, Kogure F, Obara Y, Itoi M, Kato K, Akiyama K
Department of Hygiene and Public Health, Tokyo Women's Medical College, Japan.
Jpn J Ophthalmol. 1993;37(4):467-77.
A hospital-based case-control study of senile cataract was conducted in Japan from 1988 to 1990. Two hundred and twelve patients with senile cataract and 212 control subjects with the same age-sex distribution were interviewed and given an ophthalmological examination. Both groups were randomly selected outpatients from 9 hospitals. Associations between senile cataract and four groups of variables, factors regarded as risks, life style habits, general aging indices or other factors were analyzed, and the data was subjected to statistical analysis. An increased risk of cataract was found in males who were presently spending 7 hours or more outside daily (Odds ratio = 5.07) and in females with 4 or fewer remaining teeth (Odds ratio = 2.03). The findings from this study suggest that there may be a sex-related host sensitivity or life style which is predisposing to the development of senile cataract.
1988年至1990年，日本开展了一项基于医院的老年白内障病例对照研究。研究人员对212名老年白内障患者和212名年龄与性别分布相同的对照对象进行了访谈并进行眼科检查。两组均为从9家医院随机选取的门诊患者。分析了老年白内障与四组变量（被视为风险因素、生活方式习惯、一般衰老指标或其他因素）之间的关联，并对数据进行了统计分析。结果发现，目前每天在户外活动7小时或更长时间的男性患白内障的风险增加（优势比=5.07），而剩余牙齿为4颗或更少的女性患白内障的风险增加（优势比=2.03）。该研究结果表明，可能存在与性别相关的宿主易感性或生活方式，这易导致老年白内障的发生。
