Badrinath S S, Sharma T, Biswas J, Srinivas V
Sankara Nethralaya Vision Research Foundation, Madras.
Indian J Ophthalmol. 1996 Dec;44(4):213-7.
A case-control study (244 cases and 264 controls) was done during 1986-89 on a hospital based population to evaluate the risk factors associated with the etiology of senile cataract. Patient with age between 40-60 years, visual acuity of 6/9 or less, and presence of lenticular opacity of senile origin were included as cases. Age matched individuals with absence of lenticular opacity made up the controls. Multivariate logistic regression analysis revealed that higher systolic BP and number of meals were significantly (P < or = 0.05) associated with presence of senile cataract; whereas higher weight, education and income, and utilization of cooking water had a significant protective effect against senile cataract. The present study helps the clinician to understand the possible risk factors associated with the development of senile cataract and could be helpful in designing a intervention strategy in future.
1986年至1989年期间，针对某医院人群开展了一项病例对照研究（244例病例和264例对照），以评估与老年性白内障病因相关的危险因素。年龄在40至60岁之间、视力为6/9或更低且存在老年性晶状体混浊的患者被纳入病例组。年龄匹配且无晶状体混浊的个体组成对照组。多因素逻辑回归分析显示，收缩压升高和进餐次数与老年性白内障的存在显著相关（P≤0.05）；而体重增加、受教育程度和收入提高以及使用烹饪水对老年性白内障有显著的保护作用。本研究有助于临床医生了解与老年性白内障发生相关的可能危险因素，并可能有助于未来设计干预策略。
