Popovsky M A, McCarthy S, Hawkins R E
American Red Cross Blood Services, Dedham, Massachusetts.
Transfusion. 1994 Mar;34(3):253-4. doi: 10.1046/j.1537-2995.1994.34394196625.x.
Serious complications of blood donation are rare. Reported here is a significant vascular event that resulted from whole-blood phlebotomy and required surgical repair.
A 49-year-old woman donated whole blood without incident in November 1992, but reported ecchymosis and tenderness in the antecubital area of the right arm immediately following the procedure (her medical history was unremarkable). Over the next several days, the ecchymosis extended to the axilla and she complained of numbness in all her fingers, particularly the thumb and adjacent two fingers of the involved side. Coincident to these findings, an egg-sized lump developed under the skin at the phlebotomy site. Her symptoms and the mass persisted for several weeks. Examination and ultrasound performed in January 1993 demonstrated a pulsatile mass over the brachial artery. The donor underwent an exploratory surgical procedure that revealed a 3.3 x 2.5 x 2.0-cm pseudoaneurysm of the brachial artery. Unlike a true aneurysm, this lesion was composed only of a blood clot that was compressing the outer wall of the artery. A pinpoint-sized hole was seen in the artery when the lesion was excised. The phlebotomy is believed to have caused blood to leak out of the artery, creating the lesion and exerting pressure on the median nerve.
Pseudoaneurysm of the femoral artery is a well-documented complication of cardiac catheterization and other invasive arterial procedures, but this is the first known reported case following blood donation. Blood collectors should be made aware of this potentially serious complication of blood donation.
献血的严重并发症很罕见。本文报告了一例因全血采集导致的严重血管事件,该事件需要手术修复。
一名49岁女性于1992年11月顺利捐献全血,但在采血后立即报告右臂肘前区出现瘀斑和压痛(她的病史无异常)。在接下来的几天里,瘀斑蔓延至腋窝,她抱怨所有手指麻木,尤其是患侧的拇指及相邻的两个手指。与这些发现同时出现的是,采血部位的皮肤下出现了一个鸡蛋大小的肿块。她的症状和肿块持续了几周。1993年1月进行的检查和超声显示肱动脉上方有一个搏动性肿块。捐献者接受了探查性手术,结果发现肱动脉有一个3.3×2.5×2.0厘米的假性动脉瘤。与真性动脉瘤不同,这个病变仅由一个血凝块组成,该血凝块正在压迫动脉外壁。切除病变时,在动脉上可见一个针尖大小的孔。据信采血导致血液从动脉中漏出,形成了病变并对正中神经施加了压力。
股动脉假性动脉瘤是心脏导管插入术和其他侵入性动脉操作的一种有充分记录的并发症,但这是已知的首例献血后报告病例。采血人员应了解献血这一潜在的严重并发症。