Krause A, Gerber B
Universitäts-Frauenklinik Rostock.
Zentralbl Gynakol. 1994;116(1):44-7.
Report about 8 patients with endometrial pathology during tamoxifen therapy: 1 endometrial cancer, 1 adenomyosis uteri and 6 endometrial polyps. The knowledge about effects of tamoxifen on endometrium and possibilities of prevention are discussed. Sonographic screening of patients during tamoxifen therapy and if need by endometrial biopsy is necessary especially if tamoxifen is given longer than 2 years. No more than 30 mg should given in adjuvant therapy.
关于他莫昔芬治疗期间8例子宫内膜病变患者的报告：1例子宫内膜癌、1例子宫腺肌病和6例子宫内膜息肉。讨论了关于他莫昔芬对子宫内膜的影响及预防可能性。在他莫昔芬治疗期间对患者进行超声筛查，如有必要进行子宫内膜活检是必需的，尤其是在他莫昔芬给药超过2年时。辅助治疗中给予的剂量不应超过30毫克。
