Dietrichs E, Røste G K, Røste L S, Qvist H L, Haines D E
Department of Neurology, National Hospital, Oslo, Norway.
Arch Ital Biol. 1994 Jan;132(1):25-38.
The hypothalamic projection to the cerebellar nuclei and cortex in the cat was studied by means of retrograde transport of wheat germ agglutinin-horseradish peroxidase complex and various fluorescent tracers. The hypothalamocerebellar nuclear projection originates from various parts of the posterior hypothalamus and reaches mainly the ipsilateral fastigial and interposed nuclei, but all nuclei receive some hypothalamocerebellar fibres. It appears from our double labelling experiments that at least one half of the hypothalamocerebellar nuclear neurones by means of axon collaterals also projects to the cerebellar cortex. Experiments with depositions of fluorescent tracers in both cerebellar hemispheres show that some hypothalamocerebellar fibres branch to reach different parts of the cerebellar cortex. Previous studies have shown that hypothalamocerebellar axons may be branches of hypothalamic efferents to other sites. However, experiments with combined fluorescent tracer depositions in the cerebellum and hippocampus gave no evidence for hypothalamic neurones with axon collaterals to both these regions.
采用小麦胚凝集素-辣根过氧化物酶复合物逆行运输法及多种荧光示踪剂，对猫下丘脑至小脑核团及皮质的投射进行了研究。下丘脑至小脑核团的投射起源于下丘脑后部的不同部位，主要到达同侧顶核和间位核，但所有核团均接受一些下丘脑至小脑的纤维。我们的双重标记实验表明，至少一半的下丘脑至小脑核团神经元通过轴突侧支也投射至小脑皮质。在双侧小脑半球注射荧光示踪剂的实验显示，一些下丘脑至小脑的纤维会分支至小脑皮质的不同部位。先前的研究表明，下丘脑至小脑的轴突可能是下丘脑至其他部位传出纤维的分支。然而，在小脑和海马联合注射荧光示踪剂的实验未发现下丘脑神经元有轴突侧支至这两个区域的证据。
