Dietrichs E, Zheng Z H
Brain Res. 1984 Apr 2;296(2):225-31. doi: 10.1016/0006-8993(84)90060-x.
Retrograde transport of fluorescent tracer molecules (Fast Blue and Nuclear Yellow) was used to restudy the feline hypothalamo-cerebellar and hypothalamo-spinal projections in order to decide whether hypothalamo-cerebellar and hypothalamo-spinal fibers are branches of the same axons. The finding of a significant hypothalamo-cerebellar projection from lateral, dorsal and posterior hypothalamic areas is confirmed. Scattered hypothalamo-cerebellar fibers were found to come from the supraoptic, dorsomedial, periventricular, infundibular and paraventricular nuclei, tuber cinereum and the anterior hypothalamic area. A topographical organization is proposed for the hypothalamo-cerebellar projection; the cerebellar anterior lobe receives fibers mainly from the rostral (anterior) hypothalamus while the posterior lobe receives fibers mainly from its caudal (posterior) part. The hypothalamo-spinal pathway originates principally within the dorsal, posterior and lateral hypothalamic areas, but receives small contributions also from the periventricular and paraventricular nuclei, tuber cinereum and the anterior hypothalamic area. Hypothalamic neurons retrogradely labeled from the spinal cord and from cerebellum were often located adjacent to each other, but only few double labeled neurons were found. This indicates that spinal and cerebellar projecting cells are mainly two different populations.
利用荧光示踪分子（快蓝和核黄）的逆行运输来重新研究猫的下丘脑 - 小脑和下丘脑 - 脊髓投射，以确定下丘脑 - 小脑纤维和下丘脑 - 脊髓纤维是否为同一轴突的分支。已证实存在从下丘脑外侧、背侧和后部区域发出的显著的下丘脑 - 小脑投射。发现散在的下丘脑 - 小脑纤维来自视上核、背内侧核、室周核、漏斗核、室旁核、灰结节和下丘脑前部区域。提出了下丘脑 - 小脑投射的拓扑组织；小脑前叶主要接收来自下丘脑前部（嘴侧）的纤维，而后叶主要接收来自其尾部（后部）的纤维。下丘脑 - 脊髓通路主要起源于下丘脑背侧、后部和外侧区域，但也从小室周核、室旁核、灰结节和下丘脑前部区域接收少量纤维。从脊髓和小脑逆行标记的下丘脑神经元常常彼此相邻，但仅发现少数双标记神经元。这表明投射到脊髓和小脑的细胞主要是两个不同的群体。
