Zima T, Novák L, Stípek S
First Department of Medical Chemistry and Biochemistry, School of Medicine I, Charles University, Prague, Czech Republic.
Alcohol Alcohol. 1993 Nov;28(6):693-4.
The acute administration of ethanol by gastric catheter significantly increases the plasma xanthine oxidase activity in both rats and hamsters without changing other enzyme activities--alanine aminotransferase and aspartate aminotransferase. The plasma xanthine oxidase level seems to be a sensitive marker of liver damage. Its higher activity due to the acute ethanol intoxication may have an impact on ethanol organ damage.
通过胃导管急性给予乙醇可显著提高大鼠和仓鼠的血浆黄嘌呤氧化酶活性，而不改变其他酶活性——丙氨酸转氨酶和天冬氨酸转氨酶。血浆黄嘌呤氧化酶水平似乎是肝损伤的一个敏感标志物。急性乙醇中毒导致其活性升高可能会对乙醇所致器官损伤产生影响。
