Boo N Y, Chor C Y
Department of Paediatrics, Faculty of Medicine, National University of Malaysia, Kuala Lumpur.
J Paediatr Child Health. 1994 Feb;30(1):23-7. doi: 10.1111/j.1440-1754.1994.tb00560.x.
A study carried out in the Maternity Hospital, Kuala Lumpur over a 6 year period from 1986 to 1991, showed that the annual rates of septicaemia ranged from 5.2 to 10.2/100 admissions. Septicaemia accounted for between 11.0 to 30.4% of all neonatal deaths. The case fatality ratios ranged from 23.0 to 52.2%, being highest in 1989 when basic facilities were compromised. Low birthweight neonates accounted for 55.5% of those with septicaemia. The most common causative organisms were Staphylococcus epidermidis and Staphylococcus aureus in 1986 and 1987, but from 1988 Klebsiella species became the most common. More than 50% of neonatal septicaemia occurred after the age of 2 days. The results of the study demonstrated the dynamism of infection control: when control measures introduced earlier were not sustained, outbreaks of nosocomial infection recurred or worsened.
1986年至1991年期间在吉隆坡妇产医院进行的一项研究表明，败血症的年发病率为每100例入院病例5.2至10.2例。败血症占所有新生儿死亡病例的11.0%至30.4%。病死率在23.0%至52.2%之间，1989年基础设施受损时病死率最高。低体重新生儿占败血症患者的55.5%。最常见的病原体在1986年和1987年是表皮葡萄球菌和金黄色葡萄球菌，但从1988年起克雷伯菌属成为最常见的病原体。超过50%的新生儿败血症发生在出生2天后。该研究结果证明了感染控制的动态性：当早期引入的控制措施无法持续时，医院感染暴发会再次发生或恶化。
