Wolf G, Wörth J, Achenbach H
Arch Microbiol. 1975 Dec 31;106(3):245-9. doi: 10.1007/BF00446530.
Streptomyces michiganensis strain Tü 1074, was isolated from a Tunesian soil sample and produces in liquid medium an antibiotic active pigment complex. Besides mitomycin A the separation of this complex yielded a nonactive phenoxazone, which hitherto has not been described in the literature. In contrary to all known phenoxazones from micro-organisms the new compound lacks a 2-amino-function. The production of this phenoxazone could be enhanced by optimizing the condtions of fermentation.
密歇根链霉菌菌株Tü 1074从突尼斯土壤样品中分离得到,在液体培养基中产生一种具有抗生素活性的色素复合物。除了丝裂霉素A外,该复合物的分离还得到了一种无活性的吩恶嗪,迄今尚未见文献报道。与所有已知的微生物来源的吩恶嗪不同,新化合物缺乏2-氨基官能团。通过优化发酵条件可以提高这种吩恶嗪的产量。