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[微生物的代谢产物。替兰霉素B(作者译)]

[Metabiolic products of microorganisms. Tirandamycin B(author's transl)].

作者信息

Hagenmaier H, Jaschke K H, Santo L, Scheer M, Zähner H

出版信息

Arch Microbiol. 1976 Aug;109(1-2):65-74. doi: 10.1007/BF00425114.

DOI:10.1007/BF00425114
PMID:962473
Abstract

Streptomyces flaveolus, strain Tü 1240 produces besides Tirandamycin A, a hitherto unknown antibiotic, which is closely related to Tirandamycin A. The new antibiotic Tirandamycin B contains one additional hydroxylgroup. Both antibiotics exhibit a similar antimicrobial spectrum and they seem to have the same mechanism of action. According to the data obtained from mass spectrometry, 13C-and 1H-NMR spectra formula II could be deduced for Tirandamycin B.

摘要

黄褐链霉菌Tü 1240菌株除了产生替拉达霉素A外,还产生一种迄今未知的抗生素,它与替拉达霉素A密切相关。新抗生素替拉达霉素B含有一个额外的羟基。两种抗生素具有相似的抗菌谱,并且它们似乎具有相同的作用机制。根据质谱、13C和1H-NMR光谱获得的数据,可以推导出替拉达霉素B的分子式II。

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