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人类与亚人类灵长类胎盘特异性蛋白质的比较研究(作者译)

[Comparative studies on placenta specific proteins in man and subhuman primates (author's transl)].

作者信息

Bohn H, Sedlacek H

出版信息

Arch Gynakol. 1975 Dec 30;220(2):105-21. doi: 10.1007/BF00667116.

DOI:10.1007/BF00667116
PMID:814878
Abstract

It is shown that in placentae and partly also in sera from pregnant monkeys (chimpanzee, baboon, rhesus monkey and cynomolgus) proteins occur which are immunochemically related to the human placental specific antigens HPL (human placental locatogen), SP1 (pregnancy specific beta1-glycoprotein), PP5 (placental protein 5) and HSAP (heat stable alkaline phosphatase). The immunochemical and physico-chemical properties of these monkey proteins are compared with those of the corresponding human proteins using gel diffusion test, immuno-electrophoresis, gel filtration and polyacrylamide gel electrophoresis. These antigens also have been localized in the tissue of human and monkey (cynomolgus) placentae by the immunofluorescent technique.

摘要

结果表明,在妊娠猴(黑猩猩、狒狒、恒河猴和食蟹猴)的胎盘以及部分血清中,存在一些蛋白质,这些蛋白质在免疫化学上与人类胎盘特异性抗原HPL(人胎盘催乳素)、SP1(妊娠特异性β1-糖蛋白)、PP5(胎盘蛋白5)和HSAP(热稳定碱性磷酸酶)相关。利用凝胶扩散试验、免疫电泳、凝胶过滤和聚丙烯酰胺凝胶电泳,将这些猴蛋白的免疫化学和物理化学性质与相应人类蛋白的性质进行了比较。通过免疫荧光技术,这些抗原也已定位在人和猴(食蟹猴)胎盘组织中。

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1
[Comparative studies on placenta specific proteins in man and subhuman primates (author's transl)].人类与亚人类灵长类胎盘特异性蛋白质的比较研究(作者译)
Arch Gynakol. 1975 Dec 30;220(2):105-21. doi: 10.1007/BF00667116.
2
[Isolation of the pregnancy specific beta-glycoprotein (SP1) and antigen-related proteins by means of immunoadsorption].通过免疫吸附法分离妊娠特异性β-糖蛋白(SP1)及抗原相关蛋白
Blut. 1976 Feb;32(2):103-13. doi: 10.1007/BF00995937.
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Comparison of the serum low density lipoprotein and of its apoprotein in the pig, rhesus monkey and baboon with that in man.猪、恒河猴和狒狒血清低密度脂蛋白及其载脂蛋白与人类血清低密度脂蛋白及其载脂蛋白的比较。
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Testis antigens of man and some other primates.
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Enzymologia. 1969 Oct 31;37(4):251-61.

引用本文的文献

1
Immunohistochemical location of proteins related to pregnancy-specific beta 1-glycoprotein (SP1) and placental tissue proteins (PP5, PP8, PP9, PP10, PP11, PP12) in the afterbirth of Cynomolgus monkeys (Macaca fascicularis).食蟹猴(猕猴属)胎盘胎膜中妊娠特异性β1-糖蛋白(SP1)及胎盘组织蛋白(PP5、PP8、PP9、PP10、PP11、PP12)的免疫组化定位
Arch Gynecol. 1981;230(3):195-204. doi: 10.1007/BF02111803.
2
Comparative study of placental protein 19, human chorionic gonadotrophin and pregnancy-specific beta 1-glycoprotein as immunohistochemical markers for extravillous trophoblast in pregnancy and trophoblastic disease.胎盘蛋白19、人绒毛膜促性腺激素和妊娠特异性β1-糖蛋白作为妊娠和滋养细胞疾病中外周滋养细胞免疫组化标志物的比较研究。
Histochemistry. 1989;93(2):167-73. doi: 10.1007/BF00315971.
3

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Arch Gynakol. 1977 Oct 28;223(3):179-86. doi: 10.1007/BF00667387.
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[Isolation of the pregnancy specific beta-glycoprotein (SP1) and antigen-related proteins by means of immunoadsorption].通过免疫吸附法分离妊娠特异性β-糖蛋白(SP1)及抗原相关蛋白
Blut. 1976 Feb;32(2):103-13. doi: 10.1007/BF00995937.
人血清蛋白的定量免疫电泳
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The heat-stable alkaline phosphatase content of human placentae.
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Composition of oxytocinase (cystine aminopeptidase). Amino acid and sugar analysis and some studies on the carbohydrate-polypeptide linkage and orientation of sialic acid.催产素酶(胱氨酸氨基肽酶)的组成。氨基酸和糖分析以及关于碳水化合物 - 多肽连接和唾液酸取向的一些研究。
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