Bohn H
Klin Wochenschr. 1975 Jun 15;53(12):547-54. doi: 10.1007/BF01468898.
The immunologic relations between mother, foetus and placenta are discussed and those antigens of the human placenta already characterized by their physico-chemical and immunochemical properties described. In diagnostics the detection and determination of placental proteins is used in pregnancy tests, for the evaluation of placental functions and the detection of malignant diseases. Antibodies to placental antigens have an abortive effect; immunization against placental specific proteins may have implications as an immunologic contraceptive method and for the immunotherapy of choriocarcinoma.
本文讨论了母亲、胎儿和胎盘之间的免疫关系,并描述了已根据其物理化学和免疫化学特性进行表征的人胎盘抗原。在诊断方面,胎盘蛋白的检测和测定可用于妊娠试验、评估胎盘功能以及检测恶性疾病。抗胎盘抗原的抗体具有流产作用,针对胎盘特异性蛋白的免疫接种可能作为一种免疫避孕方法以及用于绒毛膜癌的免疫治疗。