Sambur M B, Mel'nikov O F, Timchenko S V, Timchenko M D
Radiats Biol Radioecol. 1994 Jan-Feb;34(1):55-63.
The content of serum corticosterone so as immunological and nonspecific reactivity in rats exposed to single or fractionated gamma-radiation (0.35 Gy) were studied during 1 month. It has been revealed that corticosterone level, dynamics of absolute amount of leucocytes, lymphocytes, Rc-receptor-bearing cells in blood, relative content of FcR(+)-cells in bone marrow, spleen and peripheral lymph nodes of irradiated animals depend on the scheme of irradiation. Single irradiation didn't significantly influence natural and antibody-dependent killer cells activity and basal chemiluminescence level of polymorphonuclear cells, while the fractionated irradiation in equal dose induced considerable fluctuations of these parameters. The direction and intensity of the disturbances depend on the time after irradiation.
研究了单次或分次γ射线照射（0.35 Gy）的大鼠在1个月内血清皮质酮含量以及免疫和非特异性反应性。结果显示，照射动物血液中皮质酮水平、白细胞、淋巴细胞、Rc受体细胞绝对数量的动态变化，骨髓、脾脏和外周淋巴结中FcR(+)细胞的相对含量，均取决于照射方案。单次照射对自然杀伤细胞和抗体依赖性杀伤细胞活性以及多形核细胞的基础化学发光水平无显著影响，而相同剂量的分次照射则引起这些参数的显著波动。干扰的方向和强度取决于照射后的时间。
