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两条端侧神经缝合术及去除神经外膜的神经移植术:大鼠实验研究

Two end-to-side neurorrhaphies and nerve graft with removal of the epineural sheath: experimental study in rats.

作者信息

Viterbo F, Trindade J C, Hoshino K, Mazzoni A

机构信息

Faculdade de Medicina, Universidade Estadual Paulista/UNESP, São Paulo, Brazil.

出版信息

Br J Plast Surg. 1994 Mar;47(2):75-80. doi: 10.1016/0007-1226(94)90162-7.

DOI:10.1016/0007-1226(94)90162-7
PMID:8149062
Abstract

We have studied a new type of end-to-side nerve repair in rats. The healthy (donor) nerve was not divided but an epineural window was created. In our experiment, a nerve graft bridged the tibial nerve to the distal end of the divided peroneal nerve. Electrophysiological studies showed electrical impulses conducted through both end-to-side nerve junctions. Histological studies demonstrated axons leaving the lateral surface of the healthy (donor) nerve. Based on these observations, we suggest that end-to-side neurorrhaphy from a healthy nerve may bridge a neural deficit.

摘要

我们在大鼠身上研究了一种新型的端侧神经修复术。健康(供体)神经未被切断,而是创建了一个神经外膜窗口。在我们的实验中,一根神经移植物将胫神经与切断的腓总神经远端连接起来。电生理研究表明电冲动通过两个端侧神经连接点传导。组织学研究显示轴突从健康(供体)神经的外侧表面发出。基于这些观察结果,我们认为来自健康神经的端侧神经缝合术可能弥补神经缺损。

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