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Apomorphine increases blood glucose concentrations in Parkinson's disease.

作者信息

Tison F, Fouillet N, Henry P

机构信息

Service de Neurologie, Hôpital Pellegrin, Bordeaux, France.

出版信息

Clin Neuropharmacol. 1994 Feb;17(1):92-5.

PMID:8149364
Abstract

Data from studies indicate that blood glucose levels may be influenced by stimulation of central D1 and D2 dopamine receptors. This is modulated by central dopamine receptor status. We studied apomorphine-induced increase in blood glucose levels in Parkinson's disease compared with those in Parkinsonian syndromes unresponsive to dopaminergic drugs. Results indicate that apomorphine-induced blood glucose level increases are significant only in Parkinson's disease. As in the animal, this could possibly be explained by central dopamine receptor status.

摘要

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