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重度抑郁症还是单纯的丧亲之痛?对经历自杀事件的青少年的随访研究

Major depression or uncomplicated bereavement? A follow-up of youth exposed to suicide.

作者信息

Brent D A, Perper J A, Moritz G, Liotus L, Schweers J, Canobbio R

机构信息

Western Psychiatric Institute and Clinic, Pittsburgh, PA 15213.

出版信息

J Am Acad Child Adolesc Psychiatry. 1994 Feb;33(2):231-9. doi: 10.1097/00004583-199402000-00012.

Abstract

OBJECTIVE

To determine whether the depressive reactions experienced by youth exposed to suicide were uncomplicated bereavement or major depression by examining the longitudinal risk of recurrent major depression.

METHOD

The 121 friends and acquaintances of 26 adolescent suicide victims were followed up 1 to 18 months after an initial interview that took place around 6 months after the death of the suicide victim. A demographically similar group of 138 unexposed controls was also followed up.

RESULTS

The median duration of depression in the 37 subjects who became depressed after exposure was 8 months. The exposed group, compared with controls, had a higher rate of incident depression (RR = 1.7, 95% Cl = 1.0-2.8) during the follow-up period, even after adjustment for previous history of depression and other risk factors for depression. Within the group of exposed subjects, the rate of depression on follow-up was highest in those who developed a depressive disorder before exposure to suicide, intermediate in those who developed depression after exposure, and lowest in those who were not depressed at the first interview after exposure. There was no evidence of an increased incidence of suicide attempts in the exposed group relative to the unexposed controls on follow-up.

CONCLUSIONS

The depressive reactions observed in youth exposed to suicide are most consistent with major depressive episodes on the basis of course and risk of recurrence. Exposure to suicide was associated with an increased risk of recurrent depression but not with an increased long-term risk of suicidal behavior.

摘要

目的

通过检查复发性重度抑郁症的纵向风险,确定接触自杀事件的青少年所经历的抑郁反应是单纯的丧亲之痛还是重度抑郁症。

方法

对26名青少年自杀受害者的121名朋友和熟人在自杀受害者死亡后约6个月进行的首次访谈后1至18个月进行随访。还对138名未接触自杀事件的人口统计学特征相似的对照组进行了随访。

结果

在接触自杀事件后出现抑郁的37名受试者中,抑郁的中位持续时间为8个月。即使在对既往抑郁病史和其他抑郁风险因素进行调整后,接触组在随访期间的抑郁发病率仍高于对照组(相对危险度=1.7,95%可信区间=1.0-2.8)。在接触组中,随访时抑郁发生率在接触自杀事件前就患有抑郁症的人群中最高,在接触后出现抑郁症的人群中居中,在接触后首次访谈时未抑郁的人群中最低。随访时,没有证据表明接触组相对于未接触对照组的自杀未遂发生率增加。

结论

根据病程和复发风险,接触自杀事件的青少年中观察到的抑郁反应与重度抑郁发作最为一致。接触自杀事件与复发性抑郁症风险增加有关,但与自杀行为的长期风险增加无关。

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