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[脉冲及延长的X射线在空气和氮气中对黑腹果蝇性连锁隐性致死突变频率的影响]

[Effect of pulse and prolonged x-rays in air and in nitrogen on the frequency of sex-linked recessive lethal mutations in Drosophila melanogaster].

作者信息

Khaĭmovich T I, Stiazhkina T V, Shvarts N D

出版信息

Genetika. 1975;11(5):57-62.

PMID:815129
Abstract

The effect of X-irradiation on the frequency of recessive lethal mutations in Drosophila melanogaster sperm cells is studied. Drosophila males were X-irradiated in air and nitrogen in three units with doses rates of 4 X 10(9), 10(11) and 1.7 rad/sec at a dose of 2000 rad. It is found that the mutation frequency after the pulse irradiation was almost twice as low as that after prolonged irradiation. The oxygen effect is eliminated under pulse irradiation, and the data on pulse irradiation in air are similar to those on irradiation at a low dose rate in nitrogen. The data obtained are explained by the presence of short-lived oxygen-dependent damages which are not realized under pulse irradiation due to the lack of oxygen in the track volume.

摘要

研究了X射线照射对黑腹果蝇精子细胞中隐性致死突变频率的影响。将果蝇雄性在空气中和氮气中以4×10⁹、10¹¹和1.7拉德/秒的剂量率分三个单位进行2000拉德的X射线照射。发现脉冲照射后的突变频率几乎比长时间照射后的低两倍。在脉冲照射下消除了氧效应,空气中脉冲照射的数据与氮气中低剂量率照射的数据相似。所获得的数据可通过存在短寿命的氧依赖性损伤来解释,由于径迹体积中缺氧,这些损伤在脉冲照射下未实现。

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