Moss H A, Brouwers P, Wolters P L, Wiener L, Hersh S, Pizzo P A
Pediatric Branch, National Cancer Institute, Bethesda, Maryland.
J Pediatr Psychol. 1994 Feb;19(1):27-46. doi: 10.1093/jpepsy/19.1.27.
Developed a Q-sort procedure to assess social, emotional, and motivational behavior associated with central nervous system disease among 180 HIV-infected pediatric patients. These ratings were factor analyzed and scales were derived based on the factor structure. Younger (M age = 1.03 years) patients with HIV-associated encephalopathy were rated as more apathetic and nonsocial in their behavior than nonencephalopathic younger patients. Older (M age = 7.8 years) encephalopathic patients had significantly higher scores on scales measuring depression, autism, and irritability compared to nonencephalopathic patients from this age group. A subgroup (26 patients) showed a significant decrease in these elevated scores after a 6-month course of AZT.
开发了一种Q分类程序，以评估180名感染艾滋病毒的儿科患者中与中枢神经系统疾病相关的社会、情感和动机行为。对这些评分进行了因子分析，并根据因子结构得出量表。与无脑病的年轻患者相比，患有与艾滋病毒相关脑病的较年轻患者（平均年龄 = 1.03岁）在行为上被评为更冷漠、不爱社交。与该年龄组的无脑病患者相比，年龄较大（平均年龄 = 7.8岁）的脑病患者在测量抑郁、自闭症和易怒的量表上得分显著更高。一个亚组（26名患者）在接受6个月的齐多夫定疗程后，这些升高的分数显著下降。
