Schulte E, Fisseler-Eckhoff A, Müller K M
Institut für Pathologie, Berufsgenossenschaftliche Kliniken Bergmannsheil, Universitätsklinik Bochum.
Pathologe. 1994 Feb;15(1):22-7. doi: 10.1007/s002920050020.
Histological examination of 1660 biopsies (2-5 mm) of the synovial membrane of 317 patients were obtained by arthroscopic dissection; in 70% of all cases non-specific changes were revealed and in 30% specific changes. The findings included different stages of proliferation of the superficial layer, uncharacteristic inflammatory reactions of the stratum synoviale and fibrosis of the stroma, vascular proliferation and pseudopolypoid thickening of the synovial membrane. The histomorphological findings can only be interpreted reliably and a pathogenetic classification obtained, e.g., detritus synovialitis, rheumatoid arthritis or post-traumatic changes, if the arthroscopic findings conclude an exact documentation of the biopsy site and the clinical findings.
通过关节镜下解剖获取了317例患者滑膜的1660份活检样本（2 - 5毫米）进行组织学检查；在所有病例中，70%显示为非特异性改变，30%为特异性改变。这些发现包括表层不同阶段的增生、滑膜层非特征性炎症反应、基质纤维化、血管增生以及滑膜的假息肉样增厚。只有当关节镜检查结果能准确记录活检部位及临床发现时，组织形态学发现才能得到可靠解释并获得病因学分类，例如碎屑性滑膜炎、类风湿性关节炎或创伤后改变。
