Brandenburg U, Hochban W, Peter J H
Medizinische Poliklinik Marburg.
Pneumologie. 1993 Dec;47 Suppl 4:754-6.
Patients with obstructive sleep apnoea syndrome frequently present distinct changes in the craniofacial skeleton that result in a structural narrowing of the pharynx and promote pharyngeal collapse during sleep. The evaluation of the clinical data of patients with and without craniofacial dysmorphia reveals that mean age, mean Broca index and the number of additional diseases is decreased in patients with craniofacial dysmorphia. Young patients or patients with normal weight and OSAS usually present such skeletal changes. The number of sleep-related breathing disorders and the extent of nocturnal desaturation are also decreased in the group of patients with dysmorphia. The structure of sleep is similarly disturbed in both groups. In most cases patients with severe obstructive sleep apnoea have normal cephalometric data.
阻塞性睡眠呼吸暂停综合征患者的颅面骨骼常出现明显变化，导致咽部结构变窄，并促使睡眠期间咽部塌陷。对有和没有颅面畸形的患者临床数据评估显示，有颅面畸形的患者平均年龄、平均布罗卡指数和其他疾病数量有所减少。年轻患者或体重正常且患有阻塞性睡眠呼吸暂停的患者通常会出现此类骨骼变化。有畸形的患者组中与睡眠相关的呼吸障碍数量和夜间去饱和程度也有所降低。两组患者的睡眠结构同样受到干扰。在大多数情况下，重度阻塞性睡眠呼吸暂停患者的头影测量数据正常。
