Sher A E
Division of Otolaryngology-Head and Neck Surgery, Albany Medical College, New York.
Otolaryngol Clin North Am. 1990 Aug;23(4):593-608.
The pathophysiologic basis for obstructive sleep apnea syndrome (OSAS) is complex, involving the properties of the pharynx, the muscular forces that support its patency, and the homeostatic control mechanisms of respiration. The anatomic basis for OSAS is the skeletal structure of the head and neck as it is reflected in the soft tissue structures comprising and supporting the upper airway. Study of patients with craniofacial anomalies that result in OSAS, and application of similar study techniques to OSAS patients without apparent craniofacial anomalies, point up similarities and lead to a greater understanding of the anatomic aspects of OSAS.
阻塞性睡眠呼吸暂停综合征（OSAS）的病理生理基础很复杂，涉及咽部的特性、维持其通畅的肌肉力量以及呼吸的稳态控制机制。OSAS的解剖学基础是头颈部的骨骼结构，这在构成和支撑上呼吸道的软组织结构中得以体现。对导致OSAS的颅面畸形患者的研究，以及将类似研究技术应用于无明显颅面畸形的OSAS患者，揭示了相似之处，并加深了对OSAS解剖学方面的理解。
