Marchlewska-Koj A, Pochron E, Galewicz-Sojecka A, Galas J
Mammalian Reproduction Group, Jagiellonian University, Cracow, Poland.
Physiol Behav. 1994 Feb;55(2):317-21. doi: 10.1016/0031-9384(94)90140-6.
The reaction of reproductive system of outbred female mice to crowded conditions or electric foot shock was investigated. Both experimental factors inhibited estrous cycle, and decidual cell reaction (DCR) was observed after traumatization of uterine horns in tested animals. Further investigations showed that corpora lutea in females subjected to social stress were significantly larger than those in mice stressed by classical stressor. Also, plasma progesterone level increased only in females exposed to grouped females. These results indicate that social interaction among female mice lead to the development of typical pseudopregnancy, whereas inhibition of ovulation and DCR in females subjected to electric foot shock are not related to the increase of activity of corpora lutea.
研究了远交系雌性小鼠的生殖系统对拥挤环境或电击足底的反应。两种实验因素均抑制发情周期,并且在受试动物的子宫角受到创伤后观察到蜕膜细胞反应(DCR)。进一步的研究表明,遭受社会应激的雌性小鼠的黄体明显大于受到经典应激源刺激的小鼠。此外,血浆孕酮水平仅在暴露于群居雌性小鼠的雌性中升高。这些结果表明,雌性小鼠之间的社会互动会导致典型假孕的发生,而遭受电击足底的雌性小鼠的排卵抑制和DCR与黄体活性增加无关。