Wallace D J
Cedars-Sinai Medical Center, Los Angeles, California.
Rheum Dis Clin North Am. 1994 Feb;20(1):243-63.
Antimalarials are under-utilized, disease-modifying agents that are useful in the management of lupus erythematosus. Antimalarials can promote a remission in non-organ-threatening lupus and decrease its risk of dissemination. They are especially useful for cutaneous and inflammatory joint disease and have modest actions in improving serositis, fatigue, and cognitive dysfunction. As agents that do not depress the bone marrow or promote opportunistic infections, antimalarials have potential applications in combination with other antilupus medications and with each other.
抗疟药是未得到充分利用的病情改善药物，对红斑狼疮的治疗很有用。抗疟药可促进无器官威胁性狼疮的缓解并降低其扩散风险。它们对皮肤和炎症性关节疾病特别有用，在改善浆膜炎、疲劳和认知功能障碍方面也有一定作用。作为不抑制骨髓或引发机会性感染的药物，抗疟药有与其他抗狼疮药物联合使用以及相互联合使用的潜在应用价值。
