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系统性红斑狼疮。核糖核蛋白抗体。

Systemic lupus erythematosus. Antibodies to ribonuclear proteins.

作者信息

Reichlin M

机构信息

Department of Medicine, Oklahoma University Health Sciences Center, Oklahoma City.

出版信息

Rheum Dis Clin North Am. 1994 Feb;20(1):29-43.

PMID:8153403
Abstract

This review has emphasized that utility of measuring the autoimmune responses to several RNP antigens in the diagnosis of SLE, as well as their use in delineating clinical subsets. The future of this area lies in the definition of the pathogenetic mechanisms that link these autoimmune responses to clinical expression of disease.

摘要

本综述强调了检测针对多种核糖核蛋白(RNP)抗原的自身免疫反应在系统性红斑狼疮(SLE)诊断中的作用,以及它们在划分临床亚组中的应用。该领域的未来在于明确将这些自身免疫反应与疾病临床表型联系起来的发病机制。

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