Glatt A E
Division of Infectious Diseases, Catholic Medical Center of Brooklyn and Queens, Inc, Jamaica, NY 11432.
South Med J. 1994 Apr;87(4):429-30. doi: 10.1097/00007611-199404000-00001.
Pneumocystis carinii pneumonia has been the most common life-threatening opportunistic infection in patients with acquired immunodeficiency syndrome. With a better understanding of the natural history of HIV infection, however, we have come to realize that prophylaxis against P carinii can prevent the majority of such pneumonias. In this article, I focus on the rationale behind such prophylaxis, as well as the choices and dilemmas the clinician faces in deciding on the most appropriate therapy and when it should be instituted.
卡氏肺孢子虫肺炎一直是获得性免疫缺陷综合征患者中最常见的危及生命的机会性感染。然而，随着对HIV感染自然史的深入了解，我们逐渐认识到预防卡氏肺孢子虫感染可以预防大多数此类肺炎。在本文中，我将重点探讨这种预防措施背后的基本原理，以及临床医生在决定最合适的治疗方法及其启动时机时所面临的选择和困境。
