Wang L, Söderberg P G, Tengroth B
St. Erik's Eye Hospital, Karolinska Institute, Stockholm, Sweden.
Acta Ophthalmol (Copenh). 1993 Dec;71(6):810-8. doi: 10.1111/j.1755-3768.1993.tb08605.x.
It is concluded that measurement of visual readaptation time (RAT) using optokinetic nystagmus (OKN) is a repeatable measure of visual recovery after flash exposure. The semi-automatic method for measurement of RAT used here requires further development, but it is anticipated that the improved method will provide an efficient tool for increased understanding of the physiology of flash blindness. In this study on humans, it was found that if RAT is recorded twice on the same occasion, the second RAT is shorter. However, there was no systematic difference between RAT recordings on consecutive occasions. The newly developed semi-automatic method was found to provide RATs comparable to those obtained by manual measurement on a paper print out of EOG recordings. In RAT estimation, the variability between subjects shadows other sources of random variability. The least number of subjects needed in each group to detect a 20% alteration of RAT due to an experimental factor (alpha = 0.05, beta = 0.05) was estimated to 13 with independent groups design. For paired design < 10 are needed. OKN was elicited with a horizontally moving vertical grating. The eye movement was recorded by DC EOG. A sudden flash of green light temporarily abolished the OKN. The internal between the flash and the reappearance of OKN was measured as the RAT.
研究得出结论，使用视动性眼震（OKN）测量视觉重新适应时间（RAT）是一种可重复的闪光暴露后视觉恢复测量方法。此处使用的测量RAT的半自动方法需要进一步改进，但预计改进后的方法将为增进对闪光盲生理学的理解提供一种有效的工具。在这项针对人类的研究中，发现如果在同一时间记录两次RAT，第二次记录的RAT较短。然而，连续记录的RAT之间没有系统性差异。新开发的半自动方法所提供的RAT与通过在EOG记录的纸质打印件上手动测量获得的结果相当。在RAT估计中，个体间的变异性掩盖了其他随机变异来源。在独立组设计中，每组检测因实验因素导致RAT发生20%变化所需的最少个体数估计为13（α = 0.05，β = 0.05）。对于配对设计，所需个体数小于10。通过水平移动的垂直光栅诱发OKN。眼动由直流EOG记录。一道突然的绿光闪光会暂时消除OKN。闪光与OKN重新出现之间的间隔时间被测量为RAT。
