Sumitra S, Yesudian P
Department of Dermatology, Madras Medical College and Government General Hospital, India.
Int J Dermatol. 1993 Jun;32(6):422-3. doi: 10.1111/j.1365-4362.1993.tb02812.x.
During a study of cutaneous amyloidosis, it was noticed that a significant number of patients gave a history of friction of some kind or other, which when analyzed could be clearly related to their cutaneous pigmentation. A common feature in all these patients was the relative lack of itching when compared with others who did not give a history of friction.
We studied the role of friction in 65 patients with amyloidosis cutis and found that in 20 patients, frictional factors could be attributed to their cutaneous condition, and these latter were taken up for further study.
Histologic examination of the affected area of skin showed amyloid deposits, which could be detected by light microscopy with hematoxylin and eosin stained sections and confirmed by special stains.
The role of friction in the causation of lesions that resemble amyloidosis cutis morphologically is discussed.
在一项皮肤淀粉样变的研究中，注意到大量患者有某种形式的摩擦史，经分析这些摩擦与他们的皮肤色素沉着明显相关。与没有摩擦史的其他患者相比，所有这些患者的一个共同特征是相对缺乏瘙痒感。
我们研究了摩擦在65例皮肤淀粉样变患者中的作用，发现20例患者的摩擦因素可归因于其皮肤状况，对这20例患者进行了进一步研究。
对受累皮肤区域的组织学检查显示有淀粉样沉积，苏木精和伊红染色切片经光学显微镜检查可检测到淀粉样沉积，并用特殊染色法加以证实。
讨论了摩擦在形态上类似于皮肤淀粉样变的病变形成中的作用。
