Suzuki S
National Veterinary Assay Laboratory, Ministry of Agriculture, Forestry and Fisheries, Tokyo, Japan.
Int J Food Microbiol. 1994 Jan;21(1-2):89-105. doi: 10.1016/0168-1605(94)90203-8.
Salmonella enteritidis is a common pathogen of all species of mammals and fowls. The recent increase in the number of outbreaks of food poisoning due to S. enteritidis in man was epidemiologically analysed, and it was considered that contaminated eggs or egg products were the major source of this infection. To assist in prevention and eradication of human food poisoning many investigators have studied the pathogenicity of S. enteritidis in poultry. Gross pathological observations after natural and experimental infections with S. enteritidis in poultry revealed that this organism may cause systemic infection in chicks and laying hens accompanied by prolonged faecal shedding. Some variations in the mortality rates, clinical symptoms, faecal shedding and frequency of production of contaminated eggs were observed in the chicks and hens experimentally infected with S. enteritidis isolates. Choice of bacterial strain, phage type, age of bird and inoculum size may affect the outcome of an infection. Moreover, isolation of the organisms from the ovaries, oviducts and egg contents indicates the possibility of transovarian infection of S. enteritidis in chickens. Some virulence factors associated with S. enteritidis are also reviewed in the present paper.
肠炎沙门氏菌是所有哺乳动物和禽类的常见病原体。对近期人类因肠炎沙门氏菌导致食物中毒暴发数量的增加进行了流行病学分析，认为受污染的鸡蛋或蛋制品是这种感染的主要来源。为协助预防和根除人类食物中毒，许多研究人员研究了肠炎沙门氏菌在家禽中的致病性。在家禽自然感染和实验感染肠炎沙门氏菌后的大体病理观察表明，该菌可导致雏鸡和产蛋母鸡发生全身感染，并伴有长期排粪。在用肠炎沙门氏菌分离株进行实验感染的雏鸡和母鸡中，观察到死亡率、临床症状、排粪情况以及受污染鸡蛋产生频率存在一些差异。细菌菌株、噬菌体类型、禽龄和接种量的选择可能会影响感染结果。此外，从卵巢、输卵管和蛋内容物中分离出该菌表明鸡存在肠炎沙门氏菌经卵巢感染的可能性。本文还综述了一些与肠炎沙门氏菌相关的毒力因子。
