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[伴有巩膜继发侵犯的脉络膜恶性黑色素瘤]

[Malignant choroidal melanoma with secondary invasion of the sclera].

作者信息

Craitoiu S

机构信息

Clinica de Oftalmologie Craiova.

出版信息

Oftalmologia. 1994 Jan-Mar;38(1):32-6.

PMID:8155617
Abstract

The melanoma of the choroid is a tumour very rich in cells, with a reduced stroma. The reticular fibres and the pigmentation vary in abundance from one tumour to another and even from one area to another of the same tumour. The tumour vascularization is achieved by incompletely developed vessels with endothelium wall only, or by simple vascular lacunae in direct contact with tumoral cells, having various arrangements: tubular, in palisade, with lobular structure or in pseudo-rosettes. The great degree of malignity of the tumour and its different histopathological aspects connected with the possibility of intraorbital development and of metastasis, which impose early diagnosis and therapy, made us to present these observations.

摘要

脉络膜黑色素瘤是一种细胞丰富、间质减少的肿瘤。不同肿瘤之间甚至同一肿瘤的不同区域,网状纤维和色素沉着的丰富程度都有所不同。肿瘤血管形成是通过仅具有内皮壁的发育不完全的血管,或通过与肿瘤细胞直接接触的简单血管腔隙实现的,这些血管腔隙有多种排列方式:管状、栅栏状、具有小叶结构或呈假菊形团。该肿瘤的高度恶性及其与眶内发展和转移可能性相关的不同组织病理学特征,使得早期诊断和治疗成为必要,这促使我们呈现这些观察结果。

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