磷脂氢过氧化物谷胱甘肽过氧化物酶（PHGPx）在大鼠睾丸线粒体中的分布
Distribution of phospholipid hydroperoxide glutathione peroxidase (PHGPx) in rat testis mitochondria.
作者信息
Godeas C, Sandri G, Panfili E
机构信息
Department of Biochemistry, Biophysics and Macromolecular Chemistry, University of Trieste, Italy.
出版信息
Biochim Biophys Acta. 1994 Apr 20;1191(1):147-50. doi: 10.1016/0005-2736(94)90242-9.
The distribution of phospholipid hydroperoxide glutathione peroxidase (PHGPx) in isolated rat testis mitochondria was investigated, using a reverse sucrose density gradient centrifugation procedure for the separation of the inner and outer membranes and the contact sites between the two membranes. The results indicate that PHGPx is largely localized in the contact sites fraction. This finding might therefore suggest that the enzyme has more than just an antioxidant function.
利用反向蔗糖密度梯度离心法分离大鼠睾丸线粒体的内膜、外膜及两层膜之间的接触位点，研究了磷脂氢过氧化物谷胱甘肽过氧化物酶（PHGPx）在分离的大鼠睾丸线粒体中的分布。结果表明，PHGPx主要定位于接触位点部分。因此，这一发现可能表明该酶不仅仅具有抗氧化功能。
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