Singh A P, Maerzke S, von Deimling O, Raman R, Sperling K, Neitzel H
Institute of Human Genetics, Free University Berlin, Germany.
Chromosome Res. 1993 Nov;1(4):209-13. doi: 10.1007/BF00710126.
We have investigated the dynamics of meiotic prophase I in neonatal ovaries from different wild rodent species, from a laboratory strain of Mus musculus and from Mus musculus x Mus spretus F1 hybrids. We found that almost all stages of prophase I were regularly present in neonatal ovaries from these species and that their transcriptional activity can be assessed by [3H]-uridine incorporation, indicating that postnatal analysis of meiotic chromosomes and synapsis may be conducted as an alternative to the investigation of foetal ovaries.
我们研究了来自不同野生啮齿动物物种、小家鼠实验室品系以及小家鼠与西班牙小鼠的F1杂交种的新生卵巢中减数分裂前期I的动态变化。我们发现，这些物种的新生卵巢中几乎定期呈现减数分裂前期I的所有阶段，并且它们的转录活性可以通过[3H] - 尿苷掺入来评估，这表明对减数分裂染色体和联会的产后分析可作为研究胎儿卵巢的替代方法。
