Mølbak K, Wested N, Højlyng N, Scheutz F, Gottschau A, Aaby P, da Silva A P
Epidemiology Research Unit, Statens Seruminstitut, Copenhagen, Denmark.
J Infect Dis. 1994 Mar;169(3):581-7. doi: 10.1093/infdis/169.3.581.
A potential enteropathogen was found in 50% of 1219 diarrheal episodes and 48% of 511 asymptomatic controls in a 1-year community study of childhood diarrhea. Rotavirus (3% of episodes), Cryptosporidium species (6%), and enteropathogenic Escherichia coli (EPEC) with EPEC adherence factor (4%) were more prevalent in cases than controls. Giardia lamblia (19%) was the most prevalent organism but was not associated with diarrhea. Enterotoxigenic E. coli (12%), Strongyloides stercoralis (5%), Shigella species (2%), Entamoeba histolytica trophozoites (2%), and Vibrio cholerae (1%) were found at nonsignificantly higher rates. Salmonella and Campylobacter species were more prevalent among control infants. Cryptosporidium species and sequential infections from other pathogens caused persistent diarrhea.
在一项为期一年的儿童腹泻社区研究中，在1219例腹泻病例中有50%发现了潜在肠道病原体，在511例无症状对照中有48%发现了潜在肠道病原体。轮状病毒（占病例的3%）、隐孢子虫属（6%）以及带有肠致病性大肠杆菌黏附因子的肠致病性大肠杆菌（EPEC，4%）在病例中比在对照中更常见。蓝氏贾第鞭毛虫（19%）是最常见的病原体，但与腹泻无关。产肠毒素大肠杆菌（12%）、粪类圆线虫（5%）、志贺菌属（2%）、溶组织内阿米巴滋养体（2%）和霍乱弧菌（1%）的检出率虽略高，但无统计学意义。沙门氏菌和弯曲杆菌属在对照婴儿中更为常见。隐孢子虫属以及来自其他病原体的相继感染导致了持续性腹泻。
