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[腘动脉瘤与下肢缺血:先进行溶栓治疗]

[Popliteal aneurysm and leg ischemia: thrombolysis first].

作者信息

Rousseau H, Soula P, Joffre F

机构信息

Service de Radiologie, CHU Rangueil, Toulouse.

出版信息

J Mal Vasc. 1994;19 Suppl A:154-7.

PMID:8158076
Abstract

Popliteal aneurysms may threaten the viability of lower limbs, especially in the case of occlusion and poor run-off. In case of acute ischemia, thrombolysis can be used before surgery to clear the tibial arteries and enhance the results of subsequent bypasses. The procedure starts with an arteriography to show the arterial tree, then a recanalization is attempted. By means of a microcatheter pushed into the thrombosis, Heparin (1000 Units/h) and Urokinase (4,000 Units/h) are injected in situ. Arteriograms are repeated in order to control the placement of the catheter. Anticoagulant and fibrinolytic doses are biologically surveyed. Local and general complications are rare with the new techniques of fibrinolysis. Hemorrhagic complications following surgery are low despite the previous fibrinolytic treatment. Better success rates of bypasses, performed to relieve acute ischemic complications of popliteal aneurysms, should be achieved with this new modality of treatment.

摘要

腘动脉瘤可能会威胁下肢的生存能力,尤其是在发生闭塞且血流不畅的情况下。在急性缺血的情况下,可在手术前进行溶栓以清除胫动脉血栓,并提高后续搭桥手术的效果。该过程首先进行动脉造影以显示动脉树,然后尝试进行再通。通过将微导管插入血栓中,原位注射肝素(1000单位/小时)和尿激酶(4000单位/小时)。重复进行动脉造影以控制导管的位置。对抗凝剂和纤溶剂量进行生物学监测。采用新的纤溶技术时,局部和全身并发症很少见。尽管之前进行了纤溶治疗,但手术后出血并发症发生率较低。采用这种新的治疗方式,应能在缓解腘动脉瘤急性缺血并发症的搭桥手术中取得更高的成功率。

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