Chapman D C, Grover R, Schwartz P E
Springfield Obstetrics & Gynecology Associates S.C., Illinois.
Obstet Gynecol. 1994 May;83(5 Pt 2):879-82.
Polyembryomas are rare, immature germ cell malignancies characterized by numerous embryo-like bodies in association with mature and immature teratoma structures and primitive embryonic tissue. The purpose of this paper is to present a patient in whom surgical staging and postoperative serial tumor markers and imaging studies were used to determine management.
A 43-year-old woman with a stage IA polyembryoma was followed with serial alpha-fetoprotein and hCG assays, as well as serial abdominal and pelvic computed tomography (CT) scans, following surgical staging and a total abdominal hysterectomy and bilateral salpingo-oophorectomy. Chemotherapy was not given because the patient's tumor markers declined steadily into the normal range and imaging studies revealed no evidence of recurrent disease.
Women with polyembryomas surgically staged and confined to one ovary may be followed with serial tumor markers and diagnostic imaging techniques to avoid aggressive cytotoxic chemotherapy.
多胚瘤是罕见的未成熟生殖细胞恶性肿瘤，其特征是有许多胚胎样小体，伴有成熟和未成熟畸胎瘤结构以及原始胚胎组织。本文旨在介绍一名患者，通过手术分期、术后系列肿瘤标志物检查和影像学研究来确定治疗方案。
一名患有IA期多胚瘤的43岁女性，在接受手术分期、全腹子宫切除术和双侧输卵管卵巢切除术后，接受了系列甲胎蛋白和人绒毛膜促性腺激素检测，以及系列腹部和盆腔计算机断层扫描（CT）。未给予化疗，因为患者的肿瘤标志物稳步下降至正常范围，且影像学研究未发现复发疾病的证据。
经手术分期且局限于一侧卵巢的多胚瘤女性患者，可通过系列肿瘤标志物检查和诊断性影像学技术进行随访，以避免激进的细胞毒性化疗。
