Prömpeler H J, Madjar H, du Bois A, Lattermann U, Wilhelm C, Kommoss F, Pfleiderer A
University Hospital, Department of Obstetrics and Gynecology, Freiburg, Germany.
Acta Obstet Gynecol Scand. 1994 Apr;73(4):343-6. doi: 10.3109/00016349409015776.
The myometrial invasion depth of endometrial cancer is an important prognostic factor. The preoperative assessment is decisive for the appropriate surgical treatment. In 96 patients with endometrial cancer, the myometrial invasion depth (greater than 50% or less than 50%) was measured preoperatively using transvaginal sonography (TVS). The sonographic results were compared to the histopathological findings. A sensitivity of 93% was obtained for invasion depths greater than 50%. The predictive value of an invasion depth less than 50% was 93% as well. In 16% of the cases the invasion depth was overestimated while, in only 3% it was underestimated. The diagnostic accuracy was 81%. Forty-five patients were examined preceding a diagnostic dilatation and curettage and fifty-one were examined following a diagnostic dilatation and curettage. The diagnostic accuracy in both groups was equivalent. Using transvaginal sonography, the spread of cancer to the cervix was observed in five of the seven cases in which it was postoperatively confirmed. TVS is a valuable, non-invasive diagnostic method for patients with endometrial cancer. When the TVS data are combined with results from other preoperative tests, the prognostic information obtained provides a useful basis in choosing the appropriate therapy.
子宫内膜癌的肌层浸润深度是一个重要的预后因素。术前评估对于选择合适的手术治疗至关重要。对96例子宫内膜癌患者术前采用经阴道超声检查（TVS）测量肌层浸润深度（大于50%或小于50%），并将超声检查结果与组织病理学结果进行比较。对于浸润深度大于50%的情况，敏感性为93%。浸润深度小于50%的预测价值也为93%。在16%的病例中，浸润深度被高估，而只有3%被低估。诊断准确率为81%。45例患者在诊断性刮宫术前接受检查，51例在诊断性刮宫术后接受检查。两组的诊断准确率相当。在术后证实的7例癌症累及宫颈的病例中，经阴道超声检查观察到其中5例。TVS对于子宫内膜癌患者是一种有价值的非侵入性诊断方法。当TVS数据与其他术前检查结果相结合时，所获得的预后信息可为选择合适的治疗方法提供有用依据。
