Chung H, Caffrey M
Department of Chemistry, Ohio State University, Columbus 43210.
Biophys J. 1994 Feb;66(2 Pt 1):377-81. doi: 10.1016/s0006-3495(94)80787-8.
A neutral area surface can be defined as one whose area remains fixed upon bending. It is assumed that such a surface exists within the amphiphilic monolayers that constitute the bicontinuous cubic mesophases and that it parallels approximately the highly convoluted polar/apolar interface in such systems. Here, we report on how the neutral area surface in the cubic phase (space group Ia3d) of the hydrated monoacylglycerol, monoolein, was determined. It is located at a distance of approximately 8.8 A from the methyl terminus of the acyl chain. At 25 degrees C, the surface area per lipid molecule at the neutral area surface is 35.1 +/- 0.2 A2, which is remarkably similar to the mean cross-sectional area of hydrated monoolein in the lamellar liquid crystalline phase at this same temperature.
中性面积表面可定义为弯曲时面积保持不变的表面。假定在构成双连续立方中间相的两亲单分子层内存在这样一个表面，并且它大致平行于此类体系中高度卷曲的极性/非极性界面。在此，我们报告了如何确定水合单酰甘油单油酸酯立方相（空间群Ia3d）中的中性面积表面。它位于距酰基链甲基末端约8.8埃处。在25℃时，中性面积表面上每个脂质分子的表面积为35.1±0.2埃²，这与该温度下片层液晶相中水合单油酸酯的平均横截面积非常相似。
