[肽能系统参与调节呼吸中枢功能的机制]
[The mechanisms of the participation of the peptidergic systems in regulating respiratory center function].
作者信息
Voĭnov V A, Chichenkov O N, Chizh B A
出版信息
Fiziol Zh Im I M Sechenova. 1993 Nov;79(11):31-7.
PMID:8162104
Abstract
In experiments on different species of animals respiratory stimulating effects of naloxone, TRH and its analogue RGH 2202 during respiratory rhythmogenesis disturbances, evoked by hyperventilation of lungs, bleeding and intoxication with cyanides or opiates, were investigated. The role of opiate and NMDA receptors in respiratory centre function is discussed.
摘要
在针对不同动物物种的实验中，研究了纳洛酮、促甲状腺激素释放激素（TRH）及其类似物RGH 2202在因肺过度通气、出血以及氰化物或阿片类药物中毒所引发的呼吸节律发生紊乱期间的呼吸刺激作用。同时讨论了阿片受体和N-甲基-D-天冬氨酸（NMDA）受体在呼吸中枢功能中的作用。
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