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[不同类型应激源作用下大鼠红细胞钠钾ATP酶活性变化的动力学及机制]

[The dynamics and mechanism of changes in the erythrocyte Na, K-ATPase activity of rats under the action of different types of stressors].

作者信息

Medvedeva I A, Maslova M N

出版信息

Fiziol Zh Im I M Sechenova. 1993 Dec;79(12):28-34.

PMID:8162117
Abstract

The rat erythrocytes' Na, K-ATPase activity was found to drop under the effects of five various stresses: immobilisation, hypothermia, hyperoxia, physical strain, and physical strain against the background of fasting. An endogenous digoxin-like inhibiting agent(s) acting on the Na, K-ATPase seems to appear in the blood plasma of the animals under stress. The suggestion is corroborated by the fact that albumin-less supernatants of the stressed rats' blood plasma are able to inhibit the Na, K-ATPase in the erythrocytes of the control animals.

摘要

研究发现,在五种不同应激状态下,大鼠红细胞的钠钾ATP酶活性会下降,这五种应激状态分别是:固定、低温、高氧、体力负荷以及禁食状态下的体力负荷。应激状态下动物血浆中似乎会出现一种作用于钠钾ATP酶的内源性类地高辛抑制因子。应激大鼠血浆中去除白蛋白后的上清液能够抑制对照动物红细胞中的钠钾ATP酶,这一事实证实了上述推测。

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