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[1例促纤维增生性婴儿型节细胞胶质瘤]

[A case of desmoplastic infantile ganglioglioma].

作者信息

Tadokoro M, Ozawa T, Abe M, Shinagawa T, Sakurai T, Taguchi Y

机构信息

First Department of Pathology, School of Medicine, St. Marianna University.

出版信息

Noshuyo Byori. 1994;11(1):93-8.

PMID:8162157
Abstract

We have been experienced a rare case of large supratentorial neuroepithelial tumor with a subdural cyst originated from the left fronto-parietal lobe in a 14-month-old boy. The tumor was characterized by its voluminous size, a leptomeningeal growth pattern with intense desmoplasia and divergent astrocytic and ganglionic differentiation. Schwann cell differentiation and melanocytes were also minutely demonstrated. These histological findings are characteristic of desmoplastic infantile gangliogliomas, reported by VandenBerg et al in 1987. And this tumor tissue architecture strongly suggests the hamartomatous nature, rather than the ordinary neoplastic lesion.

摘要

我们遇到了一例罕见的幕上大型神经上皮肿瘤,该肿瘤伴有一个源于一名14个月大男孩左额顶叶的硬膜下囊肿。该肿瘤的特点是体积巨大,呈柔脑膜生长模式,伴有强烈的促纤维增生以及不同程度的星形细胞和神经节分化。还细微显示出施万细胞分化和黑素细胞。这些组织学发现是1987年VandenBerg等人报道的促纤维增生性婴儿型神经节胶质瘤的特征。并且这种肿瘤的组织结构强烈提示其错构瘤性质,而非普通的肿瘤性病变。

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