Russo F D, Silhavy T J
Dept of Genetics, University of Washington, Seattle 98195.
Trends Microbiol. 1993 Nov;1(8):306-10. doi: 10.1016/0966-842x(93)90007-e.
In many different bacteria several sensory-response functions are controlled by systems of similar design. Most consist of two proteins, one of which regulates the phosphorylation of the other in response to an environmental stimulus. Regulation is achieved by balancing opposed phosphorylation and dephosphorylation reactions against each other. Remarkably, such a system can generate a signal whose strength is independent of the concentration of either component.
在许多不同的细菌中，几种传感-反应功能由设计相似的系统控制。大多数系统由两种蛋白质组成，其中一种蛋白质会根据环境刺激调节另一种蛋白质的磷酸化。调节是通过使相反的磷酸化和去磷酸化反应相互平衡来实现的。值得注意的是，这样的系统可以产生一种信号，其强度与任何一种组分的浓度无关。
