De Castro R, Pavanello P, Dòmini R
Department of Paediatric Surgery, University of Bologna, Italy.
Br J Urol. 1994 Mar;73(3):303-7. doi: 10.1111/j.1464-410x.1994.tb07523.x.
To determine whether bladder augmentation has a role in avoiding urinary diversion in patients with exstrophy-epispadias complex (EEC), whether it can improve the lifestyle in patients who have previously undergone diversion or improve the result of any single surgical step in the staged functional reconstruction of the bladder in these patients.
From 1970 to 1991, 85 patients were treated for EEC. Between 1981 and 1991, 12 bladder augmentations were performed in 11 patients (seven girls and four boys) with bladder exstrophy, male epispadias (one case) and cloacal exstrophy (one case).
No significant early surgical complications were reported. Follow-up ranged from 18 months to 11 years. Late complications included bowel obstruction in one patient, a partial left ureteric stenosis at the level of the anastomosis with the gastric patch wall in one patient and bladder lithiasis in five patients (sigmoidocystoplasty in one and ileocystoplasties in four). No metabolic problems, no bladder perforations or malignancies were observed. The results on continence were good and, with the one exception reported, the condition of the upper urinary tract following surgery was satisfactory in all patients.
Augmentation cystoplasty is of use in the treatment of patients with bladder exstrophy when staged functional reconstruction is unsuccessful. This technique greatly reduces the indications for urinary diversion and can be used in the surgical treatment of EEC. The only disadvantage is that clean intermittent catheterization must be performed, sometimes only temporarily, but patient acceptance is usually high.
确定膀胱扩大术在避免膀胱外翻-尿道上裂综合征(EEC)患者行尿流改道方面是否有作用,能否改善既往已行尿流改道患者的生活质量,或改善这些患者膀胱分期功能重建中任何单一手术步骤的效果。
1970年至1991年,85例患者接受了EEC治疗。1981年至1991年,对11例膀胱外翻、男性尿道上裂(1例)和泄殖腔外翻(1例)患者(7例女孩和4例男孩)进行了12次膀胱扩大术。
未报告明显的早期手术并发症。随访时间为18个月至11年。晚期并发症包括1例患者发生肠梗阻,1例患者在与胃补片壁吻合处出现左输尿管部分狭窄,5例患者发生膀胱结石(1例行乙状结肠膀胱扩大术,4例行回肠膀胱扩大术)。未观察到代谢问题、膀胱穿孔或恶性肿瘤。控尿效果良好,除报告的1例例外,所有患者术后上尿路情况均令人满意。
当分期功能重建失败时,膀胱扩大术可用于治疗膀胱外翻患者。该技术大大减少了尿流改道的指征,可用于EEC的外科治疗。唯一的缺点是必须进行清洁间歇性导尿,有时只是暂时的,但患者的接受度通常较高。