Hauser-Kronberger C, Hacker G W, Albegger K, Saria A, Muss W H, Schlöhmicher-Thier J, Dietze O
Institut für Pathologische Anatomie, Landeskrankenanstalten Salzburg.
HNO. 1994 Feb;42(2):89-98.
Autonomic and peptidergic innervation of the human larynx (vocal cords, ventricular folds, epiglottis, subglottic region and recurrent nerves) was studied by application of single and double immunocytochemistry and radioimmunoassay. In all tissues investigated, immunoreactivities for a variety of regulatory peptides were detected and included vasoactive intestinal polypeptide (VIP), peptide histidine methionine (PHM), helospectin, neuropeptide Y (NPY), C-flanking peptide of NPY (C-PON), calcitonin gene-related peptide (CGRP), substance P and neurokinin A. In the recurrent nerves, only a few peptide-immunoreactive nerve fibers were found. The laryngeal region of the epiglottis and the subglottic region showed characteristic corpuscular nerves containing substance P and CGRP running underneath and within the epithelium.
通过单免疫细胞化学、双免疫细胞化学和放射免疫测定法，对人类喉部（声带、室襞、会厌、声门下区域和喉返神经）的自主神经和肽能神经支配进行了研究。在所有研究的组织中，均检测到多种调节肽的免疫反应性，包括血管活性肠肽（VIP）、组氨酸甲硫氨酸肽（PHM）、海洛肽、神经肽Y（NPY）、NPY的C端侧翼肽（C-PON）、降钙素基因相关肽（CGRP）、P物质和神经激肽A。在喉返神经中，仅发现少数肽免疫反应性神经纤维。会厌的喉部区域和声门下区域显示出特征性的小体神经，其含有P物质和CGRP，位于上皮下方和上皮内。
