Miyake S, Yoshikawa J, Yoshida K, Akasaka T, Shakudo M, Hozumi T, Takagi T, Okura H
Department of Cardiology, Kobe General Hospital.
J Cardiol. 1994 Mar-Apr;24(2):115-20.
Enhancement of pulmonary venous Doppler flow signals by intravenous injection of sonicated albumin was evaluated in 200 patients. Baseline pulsed Doppler signals were strong in 153 (77%) patients and weak in 47 patients. After injection of sonicated albumin, adequate pulsed Doppler flow signals were recorded in 44 (94%) of the 47 patients. Pulsed Doppler recordings could therefore achieve quantitative analysis in 197 patients (98%, p < 0.01). Signals were enhanced in proportion to the sonicated albumin dose (p < 0.01). No remarkable symptoms or complications were seen during and after examinations. Intravenous sonicated albumin improves transthoracic pulsed Doppler imaging of pulmonary venous flow. This simple and safe technique will obviate transesophageal recordings of pulmonary venous flow in adult patients and facilitate further studies of its diagnostic and monitoring value.
在200例患者中评估了静脉注射超声处理的白蛋白对肺静脉多普勒血流信号的增强作用。基线脉冲多普勒信号在153例（77%）患者中较强，在47例患者中较弱。注射超声处理的白蛋白后，47例患者中的44例（94%）记录到了足够的脉冲多普勒血流信号。因此，脉冲多普勒记录可在197例患者（98%，p<0.01）中实现定量分析。信号增强与超声处理的白蛋白剂量成比例（p<0.01）。检查期间及检查后未观察到明显症状或并发症。静脉注射超声处理的白蛋白可改善经胸肺静脉血流脉冲多普勒成像。这种简单且安全的技术将避免对成年患者进行经食管肺静脉血流记录，并有助于进一步研究其诊断和监测价值。
